Intraoperative anaphylaxis due to gelofusine in a patient undergoing intramedullary nailing of the femur: a case report
2009

Intraoperative Anaphylaxis from Gelofusine During Surgery

Sample size: 1 publication Evidence: low

Author Information

Author(s): Polyzois Ioannis, Lampard Andrina, Mohanlal Paras, Tsiridis Evgenios, Manidakis Nikolaos, Tsiridis Eleftherios

Primary Institution: Academic Orthopaedic Unit, Leeds General Infirmary, Leeds School of Medicine

Conclusion

This case highlights the importance of recognizing and treating anaphylactic reactions during surgery, particularly those caused by gelofusine.

Supporting Evidence

  • The patient had elevated serum tryptase levels, confirming an anaphylactic reaction.
  • Allergy skin prick tests showed a positive reaction to gelofusine only.
  • This is the first published report of a severe reaction to gelofusine during an orthopaedic procedure.

Takeaway

Sometimes, patients can have severe allergic reactions to medicines used during surgery, like gelofusine. It's important for doctors to quickly notice and treat these reactions.

Methodology

The case involved a 72-year-old male patient who experienced cardiac arrest during surgery, with subsequent tests confirming anaphylaxis due to gelofusine.

Participant Demographics

72-year-old Caucasian male

Digital Object Identifier (DOI)

10.1186/1757-1626-2-12

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