Study of N-(Adamantan-1-yl)-2-chloroacetamide
Author Information
Author(s): Onajole Oluseye K., Govender Thavendran, Kruger Hendrik G., Maguire Glenn E. M.
Primary Institution: University of KwaZulu–Natal
Hypothesis
The study investigates the crystal structure of N-(Adamantan-1-yl)-2-chloroacetamide as a potential anti-tuberculosis agent.
Conclusion
The compound exhibits shorter than normal C—C bond lengths and forms an infinite chain through intermolecular hydrogen bonding.
Supporting Evidence
- The compound was synthesized as part of a study into potential anti-tuberculosis agents.
- The structure displays intermolecular N—H⋯O hydrogen bonding forming an infinite chain.
- C—C bond lengths in the adamantine skeleton are shorter than the expected length.
Takeaway
The researchers looked at a new chemical compound that might help fight tuberculosis, and they found some interesting details about its structure.
Methodology
The compound was synthesized and its crystal structure was analyzed using X-ray single-crystal diffraction.
Limitations
The crystal structure of the compound was not previously reported, which limits comparative analysis.
Digital Object Identifier (DOI)
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