The assessment value of transcranial Doppler sonography versus magnetic resonance angiography in vertebrobasilar stroke
2010

Comparing Transcranial Doppler and MRI for Stroke Assessment

Sample size: 27 publication Evidence: moderate

Author Information

Author(s): Ghorbani Abbas, Ashtari Fereshteh, Fatehi Farzad

Primary Institution: Isfahan University of Medical Sciences

Hypothesis

The study aims to determine the reliability of transcranial Doppler (TCD) in evaluating vertebrobasilar arteries compared to magnetic resonance angiography (MRA) in patients with acute vertebrobasilar stroke.

Conclusion

Transcranial Doppler was only able to differentiate between stenotic and normal patterns and could not assist in grading stenosis in vertebrobasilar stroke.

Supporting Evidence

  • Significant correlation was found between mean flow velocity and MRA grading.
  • Significant mean differences in flow velocities were observed between grade 1 and other grades of stenosis.
  • TCD performed blindly may have limited value in grading stenosis.

Takeaway

Doctors used two different tests to look at blood flow in the brain after a stroke, and found that one test was good at telling if there was a problem, but not at figuring out how bad it was.

Methodology

Patients with a clinical diagnosis of vertebrobasilar stroke underwent brain MRI, MRA, and TCD within 48 hours of admission.

Potential Biases

TCD was performed blindly without visualization of arteries, which may have affected the accuracy of the results.

Limitations

The study's findings may not be generalizable due to variations in posterior circulation and the fixed depth of TCD measurements.

Participant Demographics

Mean age of patients was 65.48 years, with 37.04% females and 62.96% males.

Statistical Information

P-Value

0.000

Statistical Significance

p<0.05

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