Case Report of Paraneoplastic Cerebellar Degeneration in Breast Cancer
Author Information
Author(s): Noorani Alia, Sadiq Zaid, Minakaran Neda, Coleman Catherine, Thomas Val A, Mokbel Kefah
Primary Institution: St George's Hospital NHS Trust, London, UK
Hypothesis
Can paraneoplastic cerebellar degeneration be a presenting symptom of breast cancer?
Conclusion
Paraneoplastic cerebellar degeneration is a rare neurological syndrome associated with breast cancer, and despite treatment of the cancer, neurological symptoms often do not improve.
Supporting Evidence
- Paraneoplastic cerebellar degeneration is a rare syndrome that can occur with breast cancer.
- The patient had high titres of anti-Yo antibodies, which are associated with this condition.
- Despite treatment for breast cancer, the patient's neurological symptoms did not improve.
Takeaway
Sometimes, people with breast cancer can have problems with their brain that make it hard to move or talk. Even if doctors treat the cancer, these brain problems might not get better.
Methodology
The case study involved clinical management, imaging studies, and histological analysis of the patient's condition.
Limitations
The study is based on a single case report, limiting the generalizability of the findings.
Participant Demographics
The patient was a 40-year-old female.
Digital Object Identifier (DOI)
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