Designing clinical trials for assessing the effects of cognitive training and physical activity interventions on cognitive outcomes: The Seniors Health and Activity Research Program Pilot (SHARP-P) Study, a randomized controlled trial
2011

Effects of Cognitive Training and Physical Activity on Brain Health in Older Adults

Sample size: 73 publication 10 minutes Evidence: moderate

Author Information

Author(s): Claudine Legault, Janine M. Jennings, Jeffrey A. Katula, Dale Dagenbach, Sarah A. Gaussoin, Kaycee M. Sink, Stephen R. Rapp, W. Jack Rejeski, Sally A. Shumaker, Mark A. Espeland

Primary Institution: Wake Forest University

Hypothesis

Can cognitive training and physical activity improve cognitive outcomes in older adults at risk for cognitive decline?

Conclusion

The study found good levels of participation and retention in cognitive and physical training interventions, but no significant improvements in cognitive function were observed after four months.

Supporting Evidence

  • Intervention attendance rates were higher in the cognitive training and combined intervention groups.
  • Retention rates exceeded 90% across all groups.
  • Four-month improvements in cognitive measures increased with age among participants assigned to physical activity training.

Takeaway

Older people can join programs to help their brain health, but just a few months of training might not show big changes in how well they think.

Methodology

The study was a single-blinded randomized controlled pilot trial with a 2 × 2 factorial design involving cognitive training and physical activity interventions over four months.

Potential Biases

The nature of the control condition may have influenced outcomes.

Limitations

The pilot trial had a modest sample size and short follow-up, and participants were predominantly Caucasian with high education levels.

Participant Demographics

Participants were community-dwelling individuals aged 70-85 years, predominantly Caucasian, with 51% women and 75% having some education beyond high school.

Statistical Information

P-Value

p=0.004

Confidence Interval

[0.30, 0.99]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2318-11-27

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