Honey and Glucantime for Treating Leishmaniasis
Author Information
Author(s): Nilforoushzadeh Mohammad Ali, Jaffary Fariba, Moradi Shahram, Derakhshan Roya, Haftbaradaran Elaheh
Primary Institution: Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Hypothesis
Does the combination of topical honey and intralesional glucantime improve treatment outcomes for cutaneous leishmaniasis compared to glucantime alone?
Conclusion
The study found that the combination of honey and glucantime was less effective than glucantime alone in treating cutaneous leishmaniasis.
Supporting Evidence
- 71.1% of patients treated with glucantime alone achieved complete cure.
- 51.1% of patients treated with both glucantime and honey achieved complete cure.
- The difference in cure rates between the two groups was statistically significant.
Takeaway
This study looked at whether putting honey on skin sores helps heal a disease called leishmaniasis. It turns out that just using a medicine called glucantime works better than using both together.
Methodology
A randomized clinical trial with 100 patients divided into two groups: one received glucantime alone and the other received glucantime with topical honey.
Limitations
The study had a dropout rate, and the efficacy of honey with standardized antibacterial activity was not evaluated.
Participant Demographics
Patients aged 7-70 years, with no significant differences in demographics between groups.
Statistical Information
P-Value
0.04
Statistical Significance
p = 0.04
Digital Object Identifier (DOI)
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