Connectivity from the ventral anterior cingulate to the amygdala is modulated by appetitive motivation in response to facial signals of aggression
2008

How Motivation Affects Brain Responses to Aggressive Faces

Sample size: 21 publication 10 minutes Evidence: moderate

Author Information

Author(s): Passamonti Luca, Rowe James B., Ewbank Michael, Hampshire Adam, Keane Jill, Calder Andrew

Primary Institution: Medical Research Council, Cognition and Brain Sciences Unit

Hypothesis

Does appetitive motivation influence the connectivity between the ventral anterior cingulate and the amygdala when viewing aggressive facial expressions?

Conclusion

The study found that higher appetitive motivation is associated with reduced negative connectivity between the ventral anterior cingulate and the amygdala when viewing aggressive faces.

Supporting Evidence

  • Participants with high reward-drive showed less negative connectivity between the ventral ACC and amygdala when viewing angry faces.
  • The study identified a significant correlation between reward-drive scores and changes in connectivity.
  • Functional MRI data indicated that the ventral ACC influences the amygdala more than vice versa.

Takeaway

Some people react differently to angry faces because of how much they want rewards, which affects how their brain connects different areas when they see those faces.

Methodology

The study used fMRI to analyze brain connectivity while participants viewed angry and neutral faces, focusing on the interaction between the ventral ACC and amygdala.

Potential Biases

Potential biases may arise from self-reported measures of personality traits and the exclusion of participants with psychiatric conditions.

Limitations

The study's findings may not generalize beyond the specific emotional expressions tested (angry vs. neutral).

Participant Demographics

21 right-handed healthy volunteers (10 females; age range 19-39; mean age 25.3 years).

Statistical Information

P-Value

p<0.005

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1016/j.neuroimage.2008.07.045

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication