Colon-available raspberry polyphenols exhibit anti-cancer effects on in vitro models of colon cancer
2007

Raspberry Extracts and Colon Cancer

publication Evidence: moderate

Author Information

Author(s): Emma M Coates, Gina Popa, Chris I Gill, Mark J McCann, Gordon J McDougall, Derek Stewart, Ian Rowland

Primary Institution: Northern Ireland Centre for Food and Health (NICHE), University of Ulster

Hypothesis

Can colon-available raspberry polyphenols inhibit stages of colon carcinogenesis in vitro?

Conclusion

Raspberry phytochemicals likely to reach the colon can inhibit several important stages in colon carcinogenesis in vitro.

Supporting Evidence

  • CARE significantly reduced DNA damage in colon cancer cells.
  • CARE inhibited the invasion of colon cancer cells in vitro.
  • CARE decreased the number of cells entering the cell cycle in colon cancer models.

Takeaway

Eating raspberries might help stop cancer from growing in your tummy by using special stuff in them that fights bad cells.

Methodology

The study used a colon-available raspberry extract (CARE) tested in various in vitro models of colon cancer to assess its anti-cancer properties.

Limitations

The study's in vitro nature may not fully replicate human digestion and absorption processes.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-3163-6-4

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication