Spatial variation in prostate cancer survival in the Northern and Yorkshire region of England using Bayesian relative survival smoothing
2008

Spatial Variation in Prostate Cancer Survival in Northern and Yorkshire, England

Sample size: 19408 publication 10 minutes Evidence: moderate

Author Information

Author(s): Lesley Fairley, David Forman, Rachael West, Sharon Manda

Primary Institution: Northern and Yorkshire Cancer Registry and Information Service

Hypothesis

How does prostate cancer survival vary across different geographic areas in Northern and Yorkshire?

Conclusion

The study found significant geographic variation in prostate cancer survival rates, influenced by age, deprivation, and period of diagnosis.

Supporting Evidence

  • Men from more deprived areas had higher excess mortality rates.
  • Older age at diagnosis was associated with higher excess mortality.
  • Survival rates improved for men diagnosed in later years.

Takeaway

This study looked at how long men with prostate cancer live in different areas, finding that where you live can affect your chances of survival.

Methodology

Bayesian spatial models were used to analyze prostate cancer survival data from a population-based cancer registry.

Potential Biases

Potential bias due to missing data on neighboring areas not included in the analysis.

Limitations

The study could not account for stage of disease at diagnosis due to lack of data.

Participant Demographics

The study included men diagnosed with prostate cancer, predominantly aged 60 and over, with a significant number from deprived areas.

Statistical Information

P-Value

0.67

Confidence Interval

95% CI 41–42

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6604757

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