Response of circulating fatty acid binding protein 4 concentration to low-intensity acute aerobic exercise is amplified in an exercise duration-dependent manner in healthy men
2024

How Exercise Duration Affects Fatty Acid Binding Protein Levels

Sample size: 12 publication 10 minutes Evidence: moderate

Author Information

Author(s): Numao Shigeharu, Uchida Ryota, Nakagaichi Masaki

Primary Institution: National Institute of Fitness and Sports in Kanoya

Hypothesis

The circulating FABP4 concentration increases immediately after acute aerobic exercise at a longer duration and low intensity, and it is higher after acute aerobic exercise at a longer duration and low intensity than at a short duration and low intensity.

Conclusion

Prolonged exercise in healthy men led to a greater increase in circulating FABP4 concentrations immediately after exercise and post-exercise.

Supporting Evidence

  • FABP4 concentrations increased significantly only in the long-duration trial immediately after exercise.
  • The increase in FABP4 concentrations was significantly higher in the long-duration trial than in the short-duration trial.
  • Body fat percentage was positively correlated with the total incremental area under the curve of circulating FABP4 concentration.

Takeaway

When you exercise longer, your body releases more of a protein called FABP4 into your blood, which is important for how your body handles fat.

Methodology

This randomized crossover study involved healthy young men completing short-duration and long-duration aerobic exercise trials, with blood samples collected to measure FABP4 concentrations.

Limitations

The study's findings may not be generalizable to women, older adults, or individuals with health conditions.

Participant Demographics

Healthy young men aged 19-24 years.

Statistical Information

P-Value

p=0.018

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/s40101-024-00379-y

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