Cyrille2: A High-Throughput Bioinformatics Pipeline System
Author Information
Author(s): Mark WEJ Fiers, Ate van der Burgt, Erwin Datema, Joost CW de Groot, Roeland CHJ van Ham
Primary Institution: Plant Research International, Wageningen, The Netherlands
Hypothesis
The Cyrille2 system is designed to provide an automated, high-throughput, easy-to-use, flexible, and extensible bioinformatics workflow management system.
Conclusion
The Cyrille2 system enables easy creation and execution of high throughput, flexible bioinformatics pipelines.
Supporting Evidence
- Cyrille2 analyzed 50 Arabidopsis BAC sequences resulting in over 735,000 objects created.
- The system is used routinely for BAC annotation in two solanaceous genome sequencing projects.
- Cyrille2 can execute complex and computationally demanding pipelines.
Takeaway
Cyrille2 is a computer program that helps scientists analyze a lot of biological data quickly and easily, like a super-smart assistant for their research.
Methodology
The Cyrille2 system consists of a web-based GUI, a Scheduler for job management, and an Executor for executing jobs on a compute cluster.
Limitations
The system may face overhead issues with large numbers of small jobs and slow XML parsing for large datasets.
Digital Object Identifier (DOI)
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