Use of Platelet Rich Plasma Gel on Wound Healing
Author Information
Author(s): Carter Marissa J., Fylling Carelyn P., Parnell Laura K. S.
Hypothesis
To better understand the use and clinical outcomes of platelet rich plasma therapy in cutaneous wounds.
Conclusion
Platelet rich plasma therapy improves complete and partial wound healing compared to standard wound care.
Supporting Evidence
- Platelet rich plasma therapy is significantly favored for complete healing in chronic wounds.
- Infection rates were lower in PRP-treated wounds compared to controls.
- Adverse events were consistently lower for PRP groups than for controls.
Takeaway
This study found that using a special gel made from a patient's own blood can help wounds heal better and faster.
Methodology
A systematic review and meta-analysis of randomized controlled trials and comparative studies on platelet rich plasma therapy for cutaneous wounds published over the last 10 years.
Potential Biases
Many RCTs were lower in quality, higher in bias, and had more serious limitations than many comparative or cohort studies.
Limitations
The quality of the eligible studies varied widely, and many had serious limitations.
Participant Demographics
Studies included various types of wounds such as chronic and acute surgical wounds.
Statistical Information
Confidence Interval
95%
Statistical Significance
p<0.05
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