Male tobacco smoke load and non-lung cancer mortality associations in Massachusetts
2008

Tobacco Smoke and Non-Lung Cancer Deaths in Massachusetts

publication 10 minutes Evidence: high

Author Information

Author(s): Bruce N Leistikow, Zubair Kabir, Gregory N Connolly, Luke Clancy, Hillel R Alpert

Primary Institution: University of California, Davis

Hypothesis

Does cumulative tobacco smoke damage correlate with non-lung cancer mortality among Massachusetts males aged 30-74 from 1979 to 2003?

Conclusion

Tobacco smoke load is likely responsible for a significant number of cancer deaths, both lung and non-lung, in Massachusetts males.

Supporting Evidence

  • Lung and non-lung cancer death rates have declined steadily since 1992.
  • The study found a strong association between lung and non-lung cancer death rates.
  • Smoking-attributable fractions for all-sites cancer deaths were estimated at 73% for all ages.

Takeaway

This study found that smoking is linked to many types of cancer deaths, not just lung cancer, showing that tobacco is a big problem for health.

Methodology

The study used linear regression to analyze lung and non-lung cancer death rates as indicators of tobacco smoke exposure.

Potential Biases

Potential biases include misclassification of smoking status and ecological fallacy in estimating individual risks.

Limitations

The findings may not apply to females or other US states, and the study does not differentiate between types of smoking exposure.

Participant Demographics

The study focused on Massachusetts males aged 30-74 years.

Statistical Information

P-Value

p<0.05

Confidence Interval

1.35–2.04

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2407-8-341

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