Light Chain Deposition Disease and Atrial Fibrillation: A Case Report
Author Information
Author(s): Fabbian Fabio, Stabellini Nevio, Sartori Sergio, Tombesi Paola, Aleotti Arrigo, Bergami Maurizio, Uggeri Simona, Galdi Adriana, Molino Christian, Catizone Luigi
Primary Institution: St. Anna Hospital, Ferrara, Italy
Hypothesis
Can light chain deposition disease present with paroxysmal atrial fibrillation as the first clinical manifestation?
Conclusion
This case suggests that acute arrhythmias associated with restrictive cardiomyopathy and impaired renal function might be related to light chain deposition disease.
Supporting Evidence
- The patient had high blood pressure and left ventricular hypertrophy.
- Her renal function rapidly worsened, leading to dialysis.
- Echocardiography showed findings consistent with restrictive cardiomyopathy.
Takeaway
A woman had heart problems because of a rare disease that usually affects the kidneys, and her heart issues showed up first as irregular heartbeats.
Methodology
The patient underwent renal biopsy, echocardiography, and treatment with thalidomide and dexamethasone.
Limitations
The initial clinical management focused on cardiovascular symptoms, delaying the correct diagnosis.
Participant Demographics
A 55-year-old woman with a history of hypertension and hypothyroidism.
Digital Object Identifier (DOI)
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