Case Report: Three Farmworkers Who Gave Birth to Infants with Birth Defects Closely Grouped in Time and Place—Florida and North Carolina, 2004–2005
2007

Birth Defects in Farmworkers' Infants Linked to Pesticide Exposure

Sample size: 3 publication Evidence: low

Author Information

Author(s): Geoffrey M. Calvert, Walter A. Alarcon, Ann Chelminski, Mark S. Crowley, Rosanna Barrett, Adolfo Correa, Sheila Higgins, Hugo L. Leon, Jane Correia, Alan Becker, Ruth H. Allen, Elizabeth Evans

Primary Institution: National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention

Hypothesis

Is there a link between pesticide exposure during pregnancy and birth defects in infants born to farmworkers?

Conclusion

The study found suggestive evidence of a potential link between pesticide exposure and birth defects, but could not establish a causal relationship.

Supporting Evidence

  • Three infants with congenital anomalies were born within 8 weeks to mothers working for the same tomato grower.
  • All three mothers worked during the critical period of organogenesis in fields treated with pesticides.
  • Regulatory inspections revealed numerous violations at the farms where the mothers worked.

Takeaway

Three mothers who worked on farms with pesticide exposure had babies with serious birth defects, which raises concerns about pesticide safety for pregnant workers.

Methodology

The study involved case reports and pesticide exposure histories collected from mothers and health departments.

Potential Biases

Information on pesticide exposure was based on company records, which may be inaccurate.

Limitations

The study could not fully characterize the birth defect risk due to incomplete data on the grower's employees and potential undetected birth defects.

Participant Demographics

All three mothers were Mexican, undocumented immigrants, and sought late prenatal care.

Digital Object Identifier (DOI)

10.1289/ehp.9647

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication