Calculation of Direct Antiretroviral Treatment Costs and Potential Cost Savings by Using Generics in the German HIV ClinSurv Cohort
2011

Cost Analysis of Antiretroviral Treatment in Germany

Sample size: 10190 publication 10 minutes Evidence: moderate

Author Information

Author(s): Matthias Stoll, Christian Kollan, Frank Bergmann, Johannes Bogner, Gerd Faetkenheuer, Carlos Fritzsche, Kirsten Hoeper, Heinz-August Horst, Jan van Lunzen, Andreas Plettenberg, Stefan Reuter, Jürgen Rockstroh, Hans-Jürgen Stellbrink, Osamah Hamouda, Barbara Bartmeyer, ClinSurv Study Group

Primary Institution: Robert Koch Institute

Hypothesis

The availability of generic drugs next to branded drugs in the same market would lead to a reduction in prices.

Conclusion

The study provides insights into the cost impacts of antiretroviral therapy and suggests potential cost-saving strategies through the use of generics.

Supporting Evidence

  • Over 21 million treatment days were covered during the study.
  • Cumulative direct costs for antiretroviral drugs were over €812 million.
  • Potential savings of 10.9% to 19.8% were identified by substituting certain drugs.
  • Direct costs of cART were lower for females compared to males.
  • Mean daily drug costs increased by 13.5% over the study period.

Takeaway

This study looked at how much it costs to treat HIV in Germany and found that using generic drugs could save a lot of money.

Methodology

The study analyzed data from 10,190 HIV-infected patients over a 13-year period, focusing on treatment costs and potential savings from generics.

Potential Biases

The cohort may not represent all HIV patients in Germany, limiting generalizability.

Limitations

The study only focuses on direct costs and does not account for indirect or intangible costs.

Participant Demographics

Approximately 80% male, 75% German born, with over 60% symptomatic according to CDC classification.

Statistical Information

P-Value

<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0023946

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