Cost-Effectiveness of Treatments for Schizophrenia in Thailand
Author Information
Author(s): Phanthunane Pudtan, Theo Vos, Harvey Whiteford, Melanie Bertram
Primary Institution: School of Population Health, the University of Queensland
Hypothesis
This study aims to determine the optimal treatment package, including drug and non-drug interventions, for schizophrenia in Thailand.
Conclusion
Generic risperidone is recommended as the first line treatment in combination with family intervention for schizophrenia.
Supporting Evidence
- Generic risperidone is more cost-effective than typical antipsychotics if produced for less than 10 baht per tablet.
- The most cost-effective treatment combination includes risperidone and family intervention.
- Clozapine should only be used for patients who do not respond to risperidone and under strict monitoring.
Takeaway
This study found that using a cheaper version of a medicine called risperidone, along with family support, is the best way to help people with schizophrenia in Thailand.
Methodology
A Markov model was used to evaluate the cost-effectiveness of various antipsychotic medications and family interventions.
Potential Biases
Potential publication bias and the assumption that trial results can be directly applied to the general health status of patients.
Limitations
The study relied on data primarily from Western countries, which may not fully apply to the Thai context.
Participant Demographics
The study included 307 individuals with schizophrenia, consisting of 279 outpatients and 28 inpatients.
Statistical Information
P-Value
p<0.05
Confidence Interval
(95% CI: dominant, 18,000)
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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