Study on Transverse Reduction Deficiencies in Infants
Author Information
Author(s): Ida Neergård Sletten, Jarkko Jokihaara, Kari Klungsøyr
Primary Institution: Oslo University Hospital
Hypothesis
What are the prevalence, infant outcomes, and gestational risk factors for transverse reduction deficiencies at or above the wrist?
Conclusion
The study found a TRDAW prevalence of 0.74/10,000, with affected infants at higher risk for being small for gestational age and having lower Apgar scores.
Supporting Evidence
- The overall TRDAW prevalence was found to be 0.74/10,000.
- Infants with TRDAW had a higher risk of being small for gestational age.
- Infants with TRDAW were three times more frequently transferred to neonatal intensive care units after delivery.
- Nine infants with TRDAW had associated anomalies, most commonly in the lower limb.
Takeaway
This study looked at babies born with a specific arm condition and found that they often have other health issues, like being smaller than expected at birth.
Methodology
The study analyzed data from the Medical Birth Registry of Norway and the CULA North Oslo Registry, comparing individuals with TRDAW to a large reference population.
Potential Biases
There may be risks of misclassification bias and exclusion of stillbirths and TOPFA cases affecting risk analyses.
Limitations
The study's main limitation is the small number of individuals with TRDAW due to its rarity, and potential misclassification of cases.
Participant Demographics
The study included 202 individuals with TRDAW, consisting of 100 males and 102 females.
Digital Object Identifier (DOI)
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