Evolution of ribonuclease H genes in prokaryotes to avoid inheritance of redundant genes
2007
Evolution of Ribonuclease H Genes in Prokaryotes
Sample size: 353
publication
Evidence: high
Author Information
Author(s): Kochiwa Hiromi, Tomita Masaru, Kanai Akio
Primary Institution: Keio University
Hypothesis
The fates of redundant genes depend on the degree of functional redundancy, and functionally redundant genes will not be inherited together.
Conclusion
The study provides evidence that RNase HI and HIII genes evolve in a mutually exclusive manner due to functional redundancy.
Supporting Evidence
- RNase HI and HIII genes do not coexist in a single genome.
- Functional redundancy contributes to the exclusion of redundant genes.
- Most bacterial species have combinations of RNase HI and HII or RNase HII and HIII.
Takeaway
This study looked at how certain genes in bacteria avoid being passed down together, which helps them adapt and survive.
Methodology
The study analyzed the molecular evolution of ribonuclease H genes in 353 prokaryotic genomes using comparative genomic and phylogenetic analyses.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website