Adult-onset Langerhans cell histiocytosis with multisystem involvement: A rare case report
2024

Rare Case of Adult-onset Langerhans Cell Histiocytosis

Sample size: 1 publication Evidence: low

Author Information

Author(s): M. Alahmad Yaman, Mukdad Omar Al, Huneity Ahmad, Sayed Sarah, Adam Renan, Al-Taie Alaa

Primary Institution: Hamad Medical Corporation, Doha, Qatar

Conclusion

This case highlights the rarity of adult-onset LCH with multisystem involvement, including musculoskeletal, salivary, and central nervous systems.

Supporting Evidence

  • LCH is a rare disorder, especially among adults.
  • The patient presented with severe back pain and neurological deficits.
  • Imaging showed T6 vertebral body collapse and soft tissue compressing the spinal cord.
  • Histopathological analysis confirmed the diagnosis of LCH.

Takeaway

A 46-year-old woman had a rare disease called Langerhans cell histiocytosis that affected her spine and other body parts, causing back pain and weakness in her legs.

Methodology

The patient underwent imaging studies, surgical intervention, and histopathological analysis.

Limitations

The case is based on a single patient, limiting generalizability.

Participant Demographics

One 46-year-old female patient.

Digital Object Identifier (DOI)

10.1016/j.radcr.2024.11.069

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