Intrauterine Exposure to Environmental Pollutants and Body Mass Index during the First 3 Years of Life
2009

Impact of Environmental Pollutants on Childhood BMI

Sample size: 138 publication 10 minutes Evidence: moderate

Author Information

Author(s): Stijn L. Verhulst, Vera Nelen, Elly Den Hond, Gudrun Koppen, Caroline Beunckens, Carl Vael, Greet Schoeters, Kristine Desager

Primary Institution: University of Antwerp

Hypothesis

Is there an association between prenatal exposure to environmental pollutants and body mass index (BMI) during early childhood?

Conclusion

Intrauterine exposure to DDE and PCBs is associated with increased BMI during early childhood.

Supporting Evidence

  • DDE levels correlated with BMI SDS, modified by maternal smoking.
  • Children of smoking mothers had higher BMI SDS at 1 year compared to nonsmoking mothers.
  • Increasing PCB concentrations were associated with higher BMI SDS values at all ages.

Takeaway

This study found that babies exposed to certain chemicals before birth may weigh more as toddlers, especially if their mothers smoked.

Methodology

A prospective birth cohort study assessing mother-infant pairs with follow-up until the children were 3 years old.

Potential Biases

Potential bias due to missing data and the inability to generalize findings to the entire Flemish population.

Limitations

The study did not record maternal weight gain during pregnancy, which could influence results.

Participant Demographics

Participants were mother-infant pairs from Flanders, Belgium, with a mean maternal age of 30.8 years.

Statistical Information

P-Value

0.03

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1289/ehp.0800003

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication