Study on Conjunctival Bacteria in Patients Receiving Eye Injections
Author Information
Author(s): de Miranda Gonçalves Luca Bongiovanni, Campos Maria Leticia Lasca Sales, Barros Guilherme Feltrin, da Veiga Glaucia Luciano, Silva Juliana Antoniali, Fonseca Fernando Luiz Affonso, Gascón Thaís Moura, de Carvalho Samantha Sanches, de Carvalho Andrea Karla Ribeiro, Fernandes Greicy Ellen Pinheiro, Lima Vagner Loduca, Lima Tiago Mirco
Primary Institution: Centro Universitário Faculdade de Medicina Do ABC/FMABC, Santo André, Brazil
Hypothesis
What is the resistance profile of conjunctival bacteria in patients treated with intravitreal injections and antibiotic prophylaxis?
Conclusion
The study found that conjunctival bacteria showed higher resistance to fluoroquinolones but were sensitive to vancomycin and third-generation cephalosporins.
Supporting Evidence
- All bacteria were sensitive to vancomycin.
- Coagulase-negative Staphylococcus sp. showed 92% penicillin resistance.
- Resistance rates for S. epidermidis were 61.3% to ciprofloxacin.
- Only one resistant sample was found among 11 tested for third-generation cephalosporins.
Takeaway
Doctors looked at the germs in the eyes of patients who got special eye injections and found that some germs were harder to treat with certain medicines.
Methodology
This was a longitudinal prospective study analyzing cultures and antibiograms from patients who received intravitreal injections and used topical antibiotics.
Limitations
The study had a small number of antibiograms performed for cephalosporins.
Participant Demographics
Participants included 50% men and 50% women, all over 18 years old.
Digital Object Identifier (DOI)
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