The Ontario Cancer Research Ethics Board: a central REB that works
2008

The Ontario Cancer Research Ethics Board: A Centralized Ethics Review Board for Cancer Trials

publication Evidence: moderate

Author Information

Author(s): Chaddah M.R.

Primary Institution: Ontario Institute for Cancer Research

Conclusion

The Ontario Cancer Research Ethics Board (ocreb) has successfully streamlined the ethics review process for cancer clinical trials in Ontario, improving efficiency and participant safety.

Supporting Evidence

  • ocreb has reduced the workload for submitters and expedited study start-up at multiple sites.
  • By August 2007, ocreb had reviewed 42 multicentre cancer protocols.
  • ocreb's centralized model is viewed as a successful approach for provincial research ethics boards.

Takeaway

The Ontario Cancer Research Ethics Board helps make cancer research faster and safer by reviewing studies for many hospitals at once.

Methodology

The ocreb was established to centralize and streamline the ethics review process for multicentre cancer trials in Ontario.

Limitations

The adoption of ocreb was slower among larger academic hospitals compared to nonacademic hospitals.

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