Optic nerve sonography in the diagnostic evaluation of adult brain injury
2008

Using Optic Nerve Sonography to Diagnose Brain Injury

Sample size: 76 publication 10 minutes Evidence: high

Author Information

Author(s): Soldatos Theodoros, Karakitsos Dimitrios, Chatzimichail Katerina, Papathanasiou Matilda, Gouliamos Athanasios, Karabinis Andreas

Primary Institution: Attikon University Hospital

Hypothesis

Do measurements of optic nerve sheath diameter correlate with intracranial pressure in brain-injured adults?

Conclusion

Optic nerve sheath diameter measurements correlate with both noninvasive and invasive intracranial pressure measurements in brain-injured adults.

Supporting Evidence

  • ONSD and estimated ICP were significantly increased in patients with severe brain injury.
  • In patients with severe brain injury, ONSD measurements correlated with invasive ICP values.
  • The best cut-off value of ONSD for predicting elevated ICP was 5.7 mm.

Takeaway

Doctors can use a special ultrasound to measure the optic nerve and check if there's too much pressure in the brain, which can help them treat patients better.

Methodology

The study involved 76 critical care patients, with measurements of optic nerve sheath diameter and intracranial pressure taken using both noninvasive and invasive methods.

Potential Biases

Potential biases include the need for trained observers and the technical limitations of the ultrasound equipment.

Limitations

The study had limitations including the exclusion of patients with certain conditions and the technical challenges of the methods used.

Participant Demographics

The study included 76 critical care patients, 58 males, with an average age of 47 years.

Statistical Information

P-Value

p<0.0001

Confidence Interval

95% CI = 0.62 to 0.90

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/cc6897

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