In vitro function of random donor platelets stored for 7 days in composol platelet additive solution
2011
Function of Platelets Stored for 7 Days in Additive Solution
Sample size: 30
publication
Evidence: moderate
Author Information
Author(s): Gupta Ashish, Chandra Tulika, Kumar Ashutosh
Primary Institution: Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India
Hypothesis
The study aims to assess the in vitro function of random donor platelets stored for 7 days in a platelet additive solution.
Conclusion
Platelet viability and aggregation were best maintained on day 7 of storage in the additive solution.
Supporting Evidence
- Platelet swirling was present in all units at 22°C on day 7.
- No evidence of bacterial contamination was found.
- Platelet count showed no significant difference in additive solution.
- Significant differences were observed in glucose and platelet aggregation without additive solution.
Takeaway
This study shows that platelets can stay healthy for a week when stored in a special solution, which is better than the usual 5 days.
Methodology
30 blood donors were studied, and platelets were prepared and stored in additive solution for 7 days at 22°C.
Participant Demographics
30 blood donors of both sexes.
Statistical Information
P-Value
<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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