Hybrid Systems of Oleogels and Probiotic-Loaded Alginate Carriers for Potential Application in Cosmetics
2024

Hybrid Systems of Oleogels and Probiotic-Loaded Alginate Carriers for Potential Application in Cosmetics

publication Evidence: moderate

Author Information

Author(s): Łętocha Anna, Miastkowska Małgorzata, Sikora Elżbieta, Michalczyk Alicja, Liszka-Skoczylas Marta, Witczak Mariusz

Primary Institution: Cracow University of Technology, Faculty of Chemical Engineering and Technology

Hypothesis

The study aims to determine whether oleogel conditions influence the survival of bacteria in alginate capsules.

Conclusion

The study found that the emulsification technique resulted in better survival rates of probiotics compared to the extrusion technique.

Supporting Evidence

  • The encapsulation efficiency for the emulsification method was 90%, while for extrusion it was 87%.
  • Probiotic survival was significantly higher in encapsulated forms compared to free cells after freeze-drying.
  • Using trehalose as a cryoprotectant improved the survival rate of probiotics during the freeze-drying process.

Takeaway

This research looks at how certain gel-like substances can help keep good bacteria alive for use in cosmetics.

Methodology

Probiotic-loaded microspheres were developed using emulsification and extrusion techniques, and their viability was tested after freeze-drying and incorporation into oleogels.

Limitations

The study suggests that further research is needed to increase the initial number of cells in the microspheres for better viability over time.

Digital Object Identifier (DOI)

10.3390/molecules29245984

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