Human rhinovirus C: a newly discovered human rhinovirus species
2010
Human Rhinovirus C: A Newly Discovered Virus
Sample size: 1200
publication
10 minutes
Evidence: moderate
Author Information
Author(s): SKP Lau, CCY Yip, PCY Woo, K-Y Yuen
Primary Institution: The University of Hong Kong
Hypothesis
What is the significance of human rhinovirus C (HRV-C) in respiratory tract infections?
Conclusion
HRV-C is a significant cause of respiratory tract infections, often unrecognized in the past.
Supporting Evidence
- HRV-C has been detected in patients worldwide, with a prevalence of 1.4–30.9%.
- HRV-C is often associated with severe respiratory diseases in both children and adults.
- HRV-C infections peak in fall or winter in temperate regions and during the rainy season in tropical areas.
- HRV-C is the predominant species among human rhinoviruses, often outnumbering HRV-A and HRV-B.
Takeaway
HRV-C is a new virus that makes many people sick, especially kids, and it was not known before.
Methodology
Literature review and genome sequence analysis.
Potential Biases
Potential bias due to the focus on symptomatic patients and lack of asymptomatic controls.
Limitations
Limited data on the incidence of co-infections and the significance of HRV-C in adults.
Participant Demographics
Patients from various countries, including children and adults.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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