Translational control of cyclins
2011
Translational Control of Cyclins
publication
Evidence: moderate
Author Information
Author(s): WYTarn, MCLai
Primary Institution: Academia Sinica, Taiwan
Hypothesis
How translational regulation of cyclins influences cell cycle progression.
Conclusion
Translational control is important for the expression of certain cyclins at specific cell cycle stages and allows cells to quickly adjust cyclin levels in response to environmental changes.
Supporting Evidence
- Translational control allows rapid and reversible alterations of protein levels in response to various physiological and pathological conditions.
- Different signaling pathways may have common targets to coordinate cell cycle regulation.
- Translational control of cyclins is crucial for the timely progression through the cell cycle.
Takeaway
Cyclins help control how cells grow and divide, and their levels can change quickly based on what’s happening around them.
Methodology
This review summarizes various mechanisms of translational control of cyclins and their impact on cell cycle progression.
Limitations
The review does not provide experimental data but summarizes existing knowledge.
Digital Object Identifier (DOI)
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