2-(N-Phenylmethanesulfonamido)ethyl 1H-pyrrole-2-carboxylate
2011
Crystal Structure of a New Compound
publication
Evidence: moderate
Author Information
Author(s): Khan Salman Tariq, Yu Peng, Nelofar Aisha, Ahmed Zaheer, Chantrapromma Suchada
Primary Institution: Pharmaceutical Research Centre, PCSIR Labs Complex, Karachi, Pakistan
Hypothesis
The title compound was synthesized as an intermediate for developing new anti-inflammatory and analgesic agents.
Conclusion
The crystal structure analysis revealed the conformation of the various groups in the compound.
Supporting Evidence
- The ethoxycarbonyl group is nearly planar and almost coplanar with the pyrrole ring.
- Centrosymmetrically related molecules are linked into dimers by pairs of N—H⋯O hydrogen bonds.
- The dimers are further connected by weak intermolecular C—H⋯O hydrogen bonds.
Takeaway
Scientists made a new chemical compound and looked at its structure to understand how it might help with pain and inflammation.
Methodology
The compound was synthesized and its crystal structure was analyzed using X-ray diffraction.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website