Cardiac magnetic resonance imaging (cMRI) as a first-line approach to subclinical heart failure in children undergoing cardiotoxic chemotherapy
2011

Using MRI to Check Heart Health in Kids Getting Cancer Treatment

Sample size: 38 publication Evidence: moderate

Author Information

Author(s): de Ville de Goyet Maƫlle, Brichard Benedicte, Pirotte Thierry, Moniotte Stephane

Primary Institution: Cliniques Saint Luc, UCL, Brussels, Belgium

Hypothesis

Can cardiac magnetic resonance imaging (cMRI) effectively evaluate cardiovascular function in children undergoing cardiotoxic chemotherapy?

Conclusion

The study indicates that cMRI can provide a detailed cardiovascular evaluation of young patients undergoing chemotherapy in a reasonable timeframe.

Supporting Evidence

  • All patients completed the study protocol within the first month of diagnosis.
  • Normal systolic biventricular volumes and function were observed in all patients.
  • Mild LV myocardial scarring was identified in some patients.
  • No significant liver or cardiac iron overload was detected.

Takeaway

Doctors can use special heart scans to check how well kids' hearts are doing when they are getting cancer treatment.

Methodology

38 children were evaluated using cMRI to assess various heart functions and iron content before starting chemotherapy.

Participant Demographics

Children with a mean age of 7.8 years, ranging from 0.3 to 17.6 years.

Digital Object Identifier (DOI)

10.1186/1532-429X-13-S1-P177

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