Global Estimate of Mesothelioma Cases
Author Information
Author(s): Park Eun-Kee, Takahashi Ken, Hoshuyama Tsutomu, Cheng Tsun-Jen, Delgermaa Vanya, Le Giang Vinh, Sorahan Tom
Primary Institution: University of Occupational and Environmental Health, Kitakyushu City, Japan
Hypothesis
Recent national burden of mesothelioma is a consequence of historical cumulative use of asbestos.
Conclusion
Globally, for every four to five reported cases of mesothelioma, one case has been overlooked.
Supporting Evidence
- Approximately 174,300 mesothelioma cases were reported in 56 countries from 1994 to 2008.
- An estimated 38,900 unreported mesothelioma cases occurred in 33 countries during the same period.
- There is a statistically significant positive relationship between cumulative asbestos use and mesothelioma mortality.
- Countries with high asbestos use are likely to have a higher burden of mesothelioma.
Takeaway
This study found that many mesothelioma cases are not reported, especially in countries that used a lot of asbestos.
Methodology
The study estimated mesothelioma cases by analyzing data on asbestos use and reported mesothelioma cases from various countries.
Potential Biases
Potential bias due to underreporting and lack of awareness in developing countries.
Limitations
The findings are based on an ecological relation, and there may be bias in extrapolating data from developed to developing countries.
Participant Demographics
Countries analyzed included both developed and developing nations, representing 82.6% of the global population in 2000.
Statistical Information
P-Value
<0.0001
Confidence Interval
36,700–41,100
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website