Evolution of endometrial cancer incidence patterns in Hong Kong: A three-decade analysis with future projections
2024

Endometrial Cancer Trends in Hong Kong

Sample size: 19214 publication 10 minutes Evidence: high

Author Information

Author(s): Ma Xinyue, Wu Xiaoming, Du Jianqiang, Sun Haifeng

Primary Institution: Xi'an Jiaotong University

Hypothesis

This study aims to evaluate the impact of demographic shifts and epidemiological factors on endometrial cancer incidence rates in Hong Kong.

Conclusion

Endometrial cancer incidence among Hong Kong women has steadily increased, primarily due to demographic aging and shifts in risk factors.

Supporting Evidence

  • Endometrial cancer cases increased from 210 in 1992 to 1250 in 2021.
  • Age-standardized incidence rates rose from 7.4 to 31.0 per 100,000 person-years from 1992 to 2021.
  • Projections estimate 1718 cases by 2030, indicating a continued upward trend.

Takeaway

More women in Hong Kong are getting endometrial cancer, and this is happening because people are getting older and some health risks are increasing.

Methodology

The study used age-period-cohort modeling and Bayesian projections based on data from the Hong Kong Cancer Registry.

Potential Biases

Potential bias in projections due to reliance on population estimates that may underestimate aging effects.

Limitations

The study does not report subtypes of endometrial cancer and lacks patient-level data on risk factor exposure.

Participant Demographics

Women diagnosed with endometrial cancer in Hong Kong from 1992 to 2021.

Statistical Information

P-Value

<0.05

Confidence Interval

95% CI: 3.10–3.67

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1016/j.heliyon.2024.e40285

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