Geographic disparities in the risk of perforated appendicitis among children in Ohio: 2001–2003
2008

Geographic Disparities in Perforated Appendicitis Risk Among Children in Ohio

Sample size: 8086 publication 10 minutes Evidence: moderate

Author Information

Author(s): Robert B Penfold, Deena J Chisolm, Benedict C Nwomeh, Kelly J Kelleher

Primary Institution: The Research Institute at Nationwide Children's Hospital

Hypothesis

Children living in rural ZIP codes where the majority of people commute to an 'urbanized area' have higher rates of perforated appendicitis than those living in rural ZIP codes where the majority commute to an 'urbanized cluster'.

Conclusion

The study found that children in rural areas with significant commuting to urbanized areas are at a higher risk of perforated appendicitis.

Supporting Evidence

  • Children treated at children's hospitals had a higher perforation rate than those treated at other hospitals.
  • Patients living in rural-UA ZIP codes were more likely to have perforated appendicitis than those in rural-UC or non-rural ZIP codes.
  • Comorbid conditions significantly increased the risk of perforation.

Takeaway

Kids who live in rural areas and travel to big cities for work are more likely to have serious problems with appendicitis than those who live in rural areas closer to smaller towns.

Methodology

The study used a retrospective analysis of hospital claims data from the Ohio Hospital Association for children aged 2 to 20 years who underwent appendectomy.

Potential Biases

The study did not account for race/ethnicity, which is known to affect perforated appendicitis risk.

Limitations

The study lacked clinical data on the actual time of delay in seeking care and could not connect individual commuting habits with perforation risk.

Participant Demographics

Children aged 2 to 20 years, with data on age, sex, and insurance type available.

Statistical Information

P-Value

p < 0.001

Confidence Interval

1.04, 4.21

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.1186/1476-072X-7-56

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