Beneficial effects of cranberry juice enriched with omega-3 fatty acids in patients with type 2 diabetic and periodontal disease: A randomized pilot clinical trial
2024

Cranberry Juice with Omega-3 Helps Diabetic Patients with Gum Disease

Sample size: 41 publication 10 minutes Evidence: moderate

Author Information

Author(s): Elnaz Ashrafzadeh, Hossein Babaei, Maryam Ravanbakhsh, Javid Ahmad Zare, Leila Maghsoumi-Norouzabad

Primary Institution: Ahvaz Jundishapur University of Medical Sciences

Hypothesis

Does cranberry juice enriched with omega-3 fatty acids improve inflammatory and oxidative stress markers in diabetic patients with periodontal disease?

Conclusion

Cranberry juice enriched with omega-3 can improve periodontal health and reduce inflammation in diabetic patients.

Supporting Evidence

  • Serum and salivary TAC increased in the group receiving cranberry juice enriched with omega-3.
  • Serum levels of IL-6 and hs-CRP decreased significantly in the same group.
  • Clinical attachment loss and pocket depth were significantly reduced in all groups after the intervention.

Takeaway

Drinking cranberry juice with omega-3 can help people with diabetes and gum disease feel better and healthier.

Methodology

Forty-one diabetic patients were divided into four groups and given different treatments for 8 weeks, with various measurements taken before and after.

Potential Biases

Potential bias due to the small sample size and the specific population studied.

Limitations

The study had a small sample size and a short duration, which may limit the generalizability of the findings.

Participant Demographics

Participants were aged 35-67 years, with a mix of male and female subjects.

Statistical Information

P-Value

0.003 for hs-CRP, 0.02 for IL-6

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.34172/japid.2024.019

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