Requirement for expert histopathological assessment of ovarian cancer and borderline tumours
2000

Importance of Accurate Diagnosis in Ovarian Tumours

Sample size: 64 publication Evidence: moderate

Author Information

Author(s): Sengupta P S, Shanks J H, Buckley C H, Ryder W D J, Davies J, Reynolds K, Slade R J, Kitchener H C, Jayson G C

Primary Institution: Cancer Research Campaign, Department of Medical Oncology, Histopathology, Medical Statistics, Gynaecology Oncology, Christie Hospital National Health Trust

Hypothesis

Histopathological assessment can change the diagnosis of ovarian tumours from carcinoma to borderline.

Conclusion

Accurate histopathological assessment can prevent unnecessary chemotherapy for many patients diagnosed with borderline ovarian tumours.

Supporting Evidence

  • 42% of patients initially diagnosed with ovarian carcinoma were later found to have borderline ovarian tumours.
  • The 6-year event-free survival rate for patients with a revised diagnosis was 70%.
  • 38.1% of patients reported a family history of epithelial cancer.

Takeaway

Doctors need to look closely at ovarian tumours to make sure they are diagnosing them correctly, which can help patients avoid unnecessary treatments.

Methodology

Histopathological review of patients diagnosed with ovarian carcinoma to assess for borderline ovarian tumours.

Participant Demographics

Patients referred with a diagnosis of ovarian carcinoma and borderline ovarian tumours.

Digital Object Identifier (DOI)

10.1054/bjoc.1999.0994

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