Late follow-up of neo-aortic dimensions and coronary arteries in adult patients after the arterial switch operation
2023

Long-term follow-up of heart surgery patients

Sample size: 81 publication Evidence: moderate

Author Information

Author(s): Verheijen Diederick B.H., Engele Leo J., Egorova Anastasia D., Stöger J. Lauran, Mertens Bart J.A., van der Palen Roel L.F., Koolbergen Dave R., Hazekamp Mark G., Jukema J. Wouter, Vliegen Hubert W., Bouma Berto J., Jongbloed Monique R.M., Kiès Philippine

Primary Institution: Leiden University Medical Center

Hypothesis

What is the prevalence of neo-aortic dilatation and coronary abnormalities in adult patients after the arterial switch operation?

Conclusion

The study found a 43% prevalence of neo-aortic dilatation and identified significant coronary abnormalities in adult patients post arterial switch operation.

Supporting Evidence

  • 43% of patients had neo-aortic dilatation.
  • 6% had an interarterial course of the coronary arteries.
  • 27% had an acute coronary take-off angle of less than 30 degrees.
  • All patients with re-interventions had significant baseline abnormalities.
  • Median follow-up duration was 6.5 years.

Takeaway

Doctors looked at heart surgery patients to see how their hearts changed over time, and they found that many had problems with their heart's shape and blood vessels.

Methodology

This was a retrospective cohort study including adult TGA-ASO patients who had at least one CT-angiography.

Potential Biases

Potential selection bias due to the retrospective nature of the study.

Limitations

The study is retrospective and may not represent all patients due to the rarity of the condition.

Participant Demographics

81 patients, 69% male, median age 21 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1016/j.ijcchd.2023.100481

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