Study of Melanoma Recurrence and Lymph Node Metastasis
Author Information
Author(s): J. Eastwood, T.G. Baker
Primary Institution: University of Bradford
Hypothesis
What combination of clinical and pathological variables best predicts lymph nodal metastasis in melanoma patients?
Conclusion
The study provides a method to assess the likelihood of melanoma recurrence to regional lymph nodes, aiding in early treatment decisions.
Supporting Evidence
- 44% of patients showed recurrence of melanoma.
- 50% of patients with recurrence developed lymph nodal metastasis within 1.1 years.
- 90% developed it within 3.8 years.
- 15 out of 19 tested variables showed significant association with lymph nodal metastasis.
Takeaway
Doctors studied 150 melanoma patients to see how likely they were to have cancer spread to their lymph nodes, helping them decide on treatment sooner.
Methodology
A prospective study using logistic regression analysis based on a Cox model to evaluate clinical and pathological variables.
Participant Demographics
66 patients with recurrence, including 19 males and 29 females, with a mean age of 52.9 years.
Statistical Information
P-Value
p<0.0001
Statistical Significance
p<0.0001
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