1000 cc Intragastric Balloon for Weight Reduction
Author Information
Author(s): A. LAVY, J. LACHTER, O. ZINDER, S. EIDELMAN
Primary Institution: Rambam Medical Center, Haifa, Israel
Hypothesis
A larger volume balloon and/or a longer duration of insertion would be more effective for weight loss than previously used methods.
Conclusion
A large intragastric balloon for a prolonged time did not assist in weight loss, although Bombesin levels changed significantly.
Supporting Evidence
- Mean weight loss after six months was only 8 kg.
- Bombesin levels were significantly lower after six months.
- Most patients regained the weight initially lost after a brief initial weight loss.
Takeaway
Doctors put a big balloon in people's stomachs to help them lose weight, but most people ended up gaining the weight back.
Methodology
Intragastric balloons were inserted endoscopically into 33 morbidly obese patients for six months, with dietary therapy provided.
Potential Biases
Patients were self-selected and highly motivated, which may not represent the general population.
Limitations
The study had a small sample size and did not include behavioral modification therapy.
Participant Demographics
33 morbidly obese patients (9 men, 24 women) with a mean age of 39 years for men and 36 years for women.
Statistical Information
P-Value
p < 0.001
Statistical Significance
p < 0.001
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