Organic Papers 2-(3,4-Dimethyl-5,5-dioxo-2H,4H-pyrazolo[4,3-c][1,2]benzothiazin-2-yl)-N′-(3-methoxybenzylidene)acetohydrazide dimethylformamide hemisolvate
2011
Synthesis and Crystal Structure of a New Compound
publication
Evidence: moderate
Author Information
Author(s): Ahmad Matloob, Siddiqui Hamid Latif, Khattak Manzoor Iqbal, Ahmad Saeed, Parvez Masood
Primary Institution: Institute of Chemistry, University of the Punjab, Lahore, Pakistan
Hypothesis
The study aims to synthesize novel bioactive molecules by fusing a pyrazole moiety with a benzothiazine nucleus.
Conclusion
The crystal structure of the synthesized compound shows a stable conformation with specific intermolecular interactions.
Supporting Evidence
- The heterocyclic thiazine ring adopts a half-chair conformation.
- The crystal structure is stabilized by weak intermolecular interactions.
- Crystals suitable for analysis were grown by slow evaporation from a solution.
Takeaway
The researchers made a new chemical compound and looked at its structure to see how it holds together.
Methodology
The compound was synthesized through refluxing a mixture of specific reactants in ethanol, followed by crystallization from dimethylformamide.
Digital Object Identifier (DOI)
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