The Associations of Dental and Periodontal Lesions with the Microvascular Complications in Patients with Type 2 Diabetes Mellitus: A Case–Control Study
2024

Dental and Gum Problems in Type 2 Diabetes Patients

Sample size: 112 publication 10 minutes Evidence: moderate

Author Information

Author(s): Mirea Adina Andreea, Ștefan Adela Gabriela, Maria Moța, Clenciu Diana, Mitrea Adina, Efrem Ion Cristian, Roșu Maria Magdalena, Protasiewicz-Timofticiuc Diana Cristina, Vladu Beatrice Elena, Gheonea Theodora Claudia, Mărășescu Felicia, Eugen Moța, Vladu Ionela Mihaela, Montecucco Fabrizio

Primary Institution: University of Medicine and Pharmacy of Craiova

Hypothesis

Is the severity of dental and periodontal lesions related to the presence of microvascular complications and glycemic control in patients with type 2 diabetes mellitus?

Conclusion

Patients with type 2 diabetes mellitus often have serious dental and gum problems, especially if they have high blood sugar and inflammation.

Supporting Evidence

  • Patients with complicated lesions had significantly higher fasting blood glucose and HbA1c levels.
  • Diabetic retinopathy was more common in patients with complicated dental lesions.
  • Diabetic peripheral neuropathy was present in 90.7% of patients with complicated lesions.

Takeaway

People with diabetes can have a lot of dental problems, and if their blood sugar is high, it can make these problems worse.

Methodology

This was a case-control study with 112 participants, half with complicated dental lesions and half with superficial lesions, matched by age and gender.

Potential Biases

Potential bias due to the study being conducted in a single hospital and the lack of a control group without dental lesions.

Limitations

The study was limited to a specific geographical area and had a small sample size, which may not represent the general population.

Participant Demographics

Participants were adults over 18 years old, diagnosed with type 2 diabetes mellitus.

Statistical Information

P-Value

<0.001

Confidence Interval

95%: 0.774–0.920

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/life14121585

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