Community Threat, Positive Parenting, and Accelerated Epigenetic Aging: Longitudinal Links from Childhood to Adolescence
2024

Community Threat, Positive Parenting, and Accelerated Epigenetic Aging

Sample size: 2039 publication 10 minutes Evidence: moderate

Author Information

Author(s): Metrailer Georgette, Tavares Karina, Ver Pault Mikayla, Lopez Adamari, Denherder Shane, Valencia Everlyn Hernandez, DiMarzio Karissa, Highlander April, Merrill Sarah M., Rojo-Wissar Darlynn M., Parent Justin

Primary Institution: University of Rhode Island

Hypothesis

Positive parenting practices at ages 3, 5, and 9 will buffer the detrimental effects of threat-based early life adversity on accelerated epigenetic aging in adolescence.

Conclusion

Positive parenting reduces the pace of epigenetic aging in low, but not high, community-threat environments.

Supporting Evidence

  • Positive parenting practices are essential in shaping children’s developmental experiences.
  • Children exposed to early life adversity often exhibit increased epigenetic age acceleration.
  • High levels of community threat weaken the effect of positive parenting on pace of aging.
  • Adolescents demonstrated the slowest epigenetic pace of aging when exposed to high levels of positive parenting and low levels of community threat.

Takeaway

Kids who have supportive parents age better biologically, especially if they don't live in dangerous neighborhoods.

Methodology

Data from the Future of Families and Child Wellbeing Study was used to examine the effects of early life adversity and positive parenting on epigenetic aging.

Potential Biases

The study's focus on a specific demographic may limit the generalizability of the findings.

Limitations

The sample was skewed towards economically disadvantaged families and may not represent the broader population.

Participant Demographics

The sample included 49.7% female, 46.7% Black, 26.5% Hispanic, and 19% White non-Hispanic children.

Statistical Information

P-Value

p<0.001

Confidence Interval

[0.006, 0.017]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1101/2024.12.23.24319484

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