Whole Grain Products, Fish and Bilberries Alter Glucose and Lipid Metabolism in a Randomized, Controlled Trial: The Sysdimet Study
2011

Effects of Whole Grains, Fish, and Berries on Metabolism

Sample size: 106 publication 10 minutes Evidence: moderate

Author Information

Author(s): Maria Lankinen, Ursula Schwab, Marjukka Kolehmainen, Jussi Paananen, Kaisa Poutanen, Hannu Mykkänen, Tuulikki Seppänen-Laakso, Helena Gylling, Matti Uusitupa, Matej Orešič

Primary Institution: VTT Technical Research Centre of Finland

Hypothesis

Can a diet rich in whole grains, fatty fish, and bilberries improve glucose and lipid metabolism in individuals with impaired glucose metabolism?

Conclusion

The study suggests that a diet rich in whole grains, low insulin response grain products, bilberries, and fatty fish can improve glucose metabolism and alter lipid profiles in individuals at high risk for type 2 diabetes.

Supporting Evidence

  • Participants in the HealthyDiet group showed a decrease in 2-hour glucose concentration.
  • The HealthyDiet group had an increase in plasma long-chain PUFAs.
  • 25 lipids changed significantly in the HealthyDiet group.
  • Self-reported diet compliance was good among participants.

Takeaway

Eating whole grains, fish, and berries can help people who have trouble with their blood sugar levels feel better and healthier.

Methodology

The study involved a 12-week dietary intervention with 106 participants who were randomized into three diet groups: HealthyDiet, Whole Grain Enriched Diet, and Control.

Potential Biases

Participants were self-reported on diet compliance, which may introduce bias.

Limitations

The study's duration may have been too short to observe all potential changes in glucose metabolism.

Participant Demographics

Participants were men and women aged 40-70 with impaired glucose metabolism and features of metabolic syndrome.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0022646

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