Postgenomic Analysis of Listeria monocytogenes
Author Information
Author(s): Uwe Kaerst, F. Baquero, M. Baumgartner, C. Buchrieser, D. Cabanes, T. Chakraborty, P. Cossart, O. Diekmann, E. Domann, O. Dussurget, F. Engelbrecht, H. Fsihi, F. Garcia-del Portillo, P. Glaser, W. Goebel, T. Hain, C. Jacquet, B. Jassal, J. Johansson, B. Joseph, J. Kreft, F. Kunst, L. Jansch, P. Martin, E. Milohanic, J.-C. Perez-Diaz, P. Rice, M. Sanchez-Ruiz, J. Schaumburg, J.-M. Soulie, M. Scortti, M. Trost, J.-A. Vazquez-Boland, H. Voss, J. Wehland
Primary Institution: GBF, Ges. f. Biotechnol. Forschung
Hypothesis
The REALIS project aims to decipher all genes required for survival and adaptation of Listeria monocytogenes in different environments.
Conclusion
The REALIS project will enhance understanding of Listeria monocytogenes and provide strategies to reduce food-borne infections.
Supporting Evidence
- Listeria monocytogenes can survive in extreme conditions like high salt and low pH.
- The project aims to understand the evolutionary relationships between pathogenic and non-pathogenic Listeria.
- High throughput strategies for transcriptome analysis and mutant generation are being developed.
Takeaway
This study looks at how a germ called Listeria can survive in tough places and make people sick, and it wants to find ways to stop that.
Methodology
The study involves gene expression analyses, transcriptomics, proteomics, and the generation of mutants to understand Listeria's survival mechanisms.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website