Growth and Mycotoxin Production by Chaetomium globosum Is Favored in a Neutral pH
2008

Growth and Mycotoxin Production by Chaetomium globosum at Different pH Levels

publication Evidence: moderate

Author Information

Author(s): Matthew R. Fogle, David R. Douglas, Cynthia A. Jumper, David C. Straus

Primary Institution: Texas Tech University Health Sciences Center

Hypothesis

Mycotoxin production is directly related to growth.

Conclusion

C. globosum grows best and produces chaetoglobosin C at a neutral pH, while sporulation is favored in acidic conditions.

Supporting Evidence

  • C. globosum can grow on potato dextrose agar with pH ranging from 4.3 to 9.4.
  • The largest colonies were observed at a neutral pH of 7.01.
  • Chaetoglobosin C was only detected at a pH of 7.01.
  • Sporulation was favored in acidic environments.

Takeaway

This study found that a fungus called C. globosum grows better and makes more toxins when the pH is neutral, but it makes spores better in acidic conditions.

Methodology

The study examined the growth of C. globosum on potato dextrose agar at various pH levels and measured colony sizes and mycotoxin production.

Limitations

The study primarily focused on artificial media and may not fully represent natural conditions.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/ijms9122357

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