Breast Cancer Prognosis and Oestrogen Receptor Status
Author Information
Author(s): L. Castagnetta, A. Traina, G. Carruba, E. Fecarotta, G. Palazzotto, R. Leake
Primary Institution: University School of Medicine, Policlinico, Palermo, Italy
Hypothesis
Does the oestrogen receptor status of involved nodes provide prognostic information for breast cancer patients?
Conclusion
Patients with oestrogen receptor positive nodes have a significantly longer survival than those with negative nodes.
Supporting Evidence
- Patients with uniformly receptor positive primary tumors had a significant survival advantage.
- Patients with ER+ nodes survived significantly longer than those with ER- nodes.
- The study included 74 consecutive breast cancer patients with involved axillary nodes.
Takeaway
This study found that knowing the hormone receptor status of breast cancer can help doctors decide how to treat patients better.
Methodology
The study analyzed oestrogen receptor status in primary tumors and involved nodes of 74 breast cancer patients.
Potential Biases
There is a potential bias as the (+ +) group was slightly older than the (- -) group.
Limitations
The study may have bias due to differences in age among patient groups.
Participant Demographics
Patients included both premenopausal and postmenopausal women with node-positive breast cancer.
Statistical Information
P-Value
p<0.008
Statistical Significance
p<0.003
Want to read the original?
Access the complete publication on the publisher's website