Analyzing Recurrence in Breast Cancer
Author Information
Author(s): Chapman J W, Fish E B, Link M A
Primary Institution: Henrietta Banting Breast Centre, Women's College Hospital, University of Toronto
Hypothesis
Can competing risks analyses provide a better understanding of factors affecting recurrence in breast cancer patients?
Conclusion
Adjuvant radiation significantly reduces local recurrence in breast cancer patients, while other factors like age and tumor size also play important roles.
Supporting Evidence
- Adjuvant radiation was associated with a reduction in local recurrence.
- Age, nodal status, and tumor size had significant associations with time to recurrence.
- For patients aged ≥ 65, only nodal status and tumor size were significantly associated with time to recurrence.
Takeaway
This study looked at how different factors affect the chances of breast cancer coming back, finding that certain treatments can help reduce the risk.
Methodology
Competing risks analyses were used to assess the effects of traditional prognostic factors on different types of first recurrence in breast cancer patients.
Participant Demographics
Cohort of primary invasive breast cancer patients accrued between 1971 and 1990, including those aged ≥ 65.
Statistical Information
P-Value
p ≤ 0.05
Statistical Significance
p ≤ 0.05
Digital Object Identifier (DOI)
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