Epithelial Cells in Bone Marrow of Oesophageal Cancer Patients
Author Information
Author(s): Thorban S, Rosenberg R, Busch R, Roder R J
Primary Institution: Department of Surgery, Institute of Medical Statistics and Epidemology, Technische Universität München
Hypothesis
The presence of epithelial cells in bone marrow is a significant prognostic factor for patients with oesophageal cancer.
Conclusion
Epithelial cells in the bone marrow of oesophageal cancer patients are a significant prognostic factor and can aid in preoperative staging and monitoring therapy.
Supporting Evidence
- 75 patients with oesophageal cancer had CK-positive cells in bone marrow.
- 29 of 75 patients (38.7%) showed CK-positive cells.
- Significant difference in overall survival time between patients with and without epithelial cells in bone marrow.
Takeaway
Doctors found that if cancer cells are in the bone marrow of patients with oesophageal cancer, it can help predict how well they will do.
Methodology
Cytokeratin-positive cells in bone marrow were detected using immunocytochemistry and correlated with prognosis factors through multivariate analysis.
Participant Demographics
Patients with squamous cell carcinoma of the oesophagus.
Statistical Information
P-Value
< 0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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