Genes Identified by Visible Mutant Phenotypes Show Increased Bias toward One of Two Subgenomes of Maize
2011

Maize Genes Show Bias Toward One Subgenome

Sample size: 464 publication Evidence: moderate

Author Information

Author(s): James C. Schnable, Michael Freeling

Primary Institution: University of California, Berkeley

Hypothesis

Do maize genes identified by visible mutant phenotypes show a bias toward one of the two subgenomes?

Conclusion

The study found that maize genes identified by mutant phenotypes are disproportionately located on the maize1 subgenome.

Supporting Evidence

  • The study identified 464 classical maize genes.
  • Maize1 genes tend to be expressed at higher levels than their duplicates on maize2.
  • The bias towards maize1 for mutant phenotype genes was statistically significant.

Takeaway

This study looked at maize genes and found that those linked to visible traits are more often found in one part of the maize genome than the other.

Methodology

The researchers manually annotated classical maize genes and compared their locations in the maize genome to those in other grass species.

Potential Biases

Potential bias in gene selection due to reliance on visible mutant phenotypes.

Limitations

The study primarily focuses on classical maize genes and may not represent all maize genes.

Statistical Information

P-Value

0.0222

Statistical Significance

p=0.0222

Digital Object Identifier (DOI)

10.1371/journal.pone.0017855

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