Did RNA editing in plant organellar genomes originate under natural selection or through genetic drift?
2008

How RNA Editing Evolved in Plant Organelles

publication Evidence: high

Author Information

Author(s): Jobson Richard W, Qiu Yin-Long

Primary Institution: Department of Ecology and Evolutionary Biology, University of Michigan

Hypothesis

Did RNA editing in plant organellar genomes originate under natural selection or through genetic drift?

Conclusion

RNA editing in plant organellar genomes is likely maintained by natural selection due to its role in enhancing protein functionality.

Supporting Evidence

  • RNA editing predominantly occurs at functionally important codon positions.
  • Editing sites are more frequent in genes encoding membrane-bound proteins.
  • Natural selection likely maintains RNA editing activity due to its functional importance.

Takeaway

Plants can change their genetic instructions after they are made, which helps them make better proteins. This study looks at how this ability started and why it matters.

Methodology

The study analyzed RNA editing patterns in chloroplast and mitochondrial genomes of various plant species to understand the origins and evolution of RNA editing.

Limitations

The study does not address the causes of lineage-specific occurrences of RNA editing sites.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1186/1745-6150-3-43

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