Peritoneal Dialysis-Associated Peritonitis Rates in Outpatient and Hospital Settings
Author Information
Author(s): Knapp Christopher MD, MPH, Li Shuling PhD, Kou Chuanyu MS, Wetmore James B. MD, Johansen Kirsten L. MD
Primary Institution: Chronic Disease Research Group, Minneapolis, MN
Hypothesis
It is unclear if the trend toward improved peritonitis hospitalization rates has been matched by improvements in outpatient peritonitis rates.
Conclusion
The burden of peritonitis has significantly decreased for individuals who perform peritoneal dialysis.
Supporting Evidence
- Hospitalization rates for peritonitis have decreased by more than 50% in the US since 2009.
- The unadjusted rate of combined peritonitis events fell from 58.1 per 100 patient-years in 2009 to 30.7 in 2018.
- The adjusted rate ratio for hospitalization with peritonitis decreased by 11% per 2-year period.
- Peritonitis rates improved universally, regardless of inpatient or outpatient setting.
Takeaway
This study found that fewer people getting peritoneal dialysis are getting sick from peritonitis, which is a serious infection, over the years.
Methodology
The study used data from the USRDS to identify a cohort of adults starting peritoneal dialysis and analyzed peritonitis events using Poisson regression models.
Limitations
The study was limited to the Medicare fee-for-service population, which is older and less diverse than the overall peritoneal dialysis population.
Participant Demographics
The average age was 64 years; 19% were Black, 65% were White, and 77% lived in urban areas.
Statistical Information
P-Value
<.001
Confidence Interval
95% CI 0.87-0.90
Statistical Significance
<.001
Digital Object Identifier (DOI)
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